Said et al reported a simple score for predicting outcomes for a patient with oral cavity cancer. This can help to identify a patient who may require more aggressive management. The authors are from Princess Margaret Cancer Centre and University of Toronto in Toronto.
Patient selection: oral cavity cancer (location but not histologic type specified; presumably mostly squamous cell carcinomas)
Parameters:
(1) pT status
(2) pathological extranodal extension
(3) engraftment of tumor samples into immunodeficient mice
Parameter
Finding
Points
pT status
pT1 or pT2
0
pT3 or pT4
1
extranodal extension
no
0
yes
1
engraftment
no
0
yes
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• A score >= 2 is high risk.
Risk Group
5-Year Locoregional Failure
5-year Distant Metastasis
low
0.265
0.084
high
0.435
0.382
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