A discriminant score can be used within 24 hours of birth to predict if a premature infant will have a symptomatic patent ductus arteriosus (PDA).
Parameters:
(1) birth weight in grams
(2) diagnosis of hyaline membrane disease
(3) diagnosis of intra-uterine growth retardation
(4) treatment with distending airway pressure during first 24 hours
(5) acute perinatal stress
Parameter |
Finding |
Value |
birth weight in grams |
|
(birth weight in grams) |
hyaline membrane disease |
present |
-456 |
|
absent |
0 |
intra-uterine growth retardation |
present |
466 |
|
absent |
0 |
treatment with distending airway pressure |
anytime during first 24 hours after birth, excluding resuscitation in the delivery room |
-220 |
|
none |
0 |
acute perinatal stress |
present |
-104 |
|
absent |
0 |
discriminant score =
= (points for birth weight) + (points for hyaline membrane disease) + (points for intra-uterine growth retardation) + (points for treatment with distending airway pressure) + (points for acute perinatal stress)
Interpretation:
• If the discriminant score > 852 then the infant is predicted not to develop a symptomatic patent ductus arteriosus.
• If the discriminant score < 852 then the infant is predicted to develop a symptomatic patent ductus arteriosus.
• If the discriminant score = 852, then cannot predict.
Score Interval (using overlapping intervals) |
Percent of Infants with Symptomatic PDA |
-100 to 300 |
75% |
100 to 500 |
87% |
300 to 700 |
87% |
500 to 900 |
70% |
700 to 1100 |
30% |
900 to 1300 |
18% |
1100 to 1500 |
7% |
1300 to 1700 |
0% |
1500 to 1900 |
0% |
1700 to 2100 |
0% |
(percents estimated from Figure 2 page 725)
Specialty: Cardiology
ICD-10: ,