Description

A discriminant score can be used within 24 hours of birth to predict if a premature infant will have a symptomatic patent ductus arteriosus (PDA).


 

Parameters:

(1) birth weight in grams

(2) diagnosis of hyaline membrane disease

(3) diagnosis of intra-uterine growth retardation

(4) treatment with distending airway pressure during first 24 hours

(5) acute perinatal stress

 

Parameter

Finding

Value

birth weight in grams

 

(birth weight in grams)

hyaline membrane disease

present

-456

 

absent

0

intra-uterine growth retardation

present

466

 

absent

0

treatment with distending airway pressure

anytime during first 24 hours after birth, excluding resuscitation in the delivery room

-220

 

none

0

acute perinatal stress

present

-104

 

absent

0

 

discriminant score =

= (points for birth weight) + (points for hyaline membrane disease) + (points for intra-uterine growth retardation) + (points for treatment with distending airway pressure) + (points for acute perinatal stress)

 

Interpretation:

• If the discriminant score > 852 then the infant is predicted not to develop a symptomatic patent ductus arteriosus.

• If the discriminant score < 852 then the infant is predicted to develop a symptomatic patent ductus arteriosus.

• If the discriminant score = 852, then cannot predict.

 

Score Interval (using overlapping intervals)

Percent of Infants with Symptomatic PDA

-100 to 300

75%

100 to 500

87%

300 to 700

87%

500 to 900

70%

700 to 1100

30%

900 to 1300

18%

1100 to 1500

7%

1300 to 1700

0%

1500 to 1900

0%

1700 to 2100

0%

(percents estimated from Figure 2 page 725)

 


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