Patients with asymptomatic aortic stenosis may progress to symptomatic disease or die suddenly. Certain risk factors seen on echocardiography can help identify patients with a poor prognosis who may benefit from early valve replacement. The authors are from Vienna General Hospital and the University of Vienna in Austria.
Ultrasound examinations:
(1) M-mode echocardiography
(2) 2-dimensional echocardiography
(3) Doppler ultrasonography
Aortic Valve Stenosis |
Features |
congenital |
2 cusps identified during systole; systolic cup doming or highly asymmetric thickening or both |
rheumatic |
commissural fusion with mitral valve stenosis |
degenerative |
thickening and increased echogenicity of the cusps (excluding the free edges) with reduced systolic opening |
Aortic Valvular Calcifications on Echocardiography |
Degree |
Grade |
none or minimal |
none |
1 |
small isolated spots (mild) |
mild |
2 |
multiple, large spots (moderate) |
moderate |
3 |
extensive thickening and calcification of the cusps |
severe |
4 |
Mitral annular calcifications defined as dense, highly reflective area at the base of the mitral valve leaflet.
increase in aortic-jet velocity in m/sec =
= ((aortic jet velocity in m/sec at first exam) – (aortic jet velocity in m/sec at second exam)) / (time in years between examinations)
where:
• The examinations are >= 6 months apart.
Risk factors for poor prognosis in patients with asymptomatic aortic stenosis:
(1) presence of moderate or severe valvular calcifications
(2) increase in mean aortic-jet velocity (>= 0.3 m per second per year)
Factors not found to be independent predictors:
(1) age
(2) sex
(3) coronary artery disease
(4) hypertension
(5) diabetes mellitus
(6) hypercholesterolemia
Specialty: Cardiology
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