Description

Patients with asymptomatic aortic stenosis may progress to symptomatic disease or die suddenly. Certain risk factors seen on echocardiography can help identify patients with a poor prognosis who may benefit from early valve replacement. The authors are from Vienna General Hospital and the University of Vienna in Austria.


 

Ultrasound examinations:

(1) M-mode echocardiography

(2) 2-dimensional echocardiography

(3) Doppler ultrasonography

Aortic Valve Stenosis

Features

congenital

2 cusps identified during systole; systolic cup doming or highly asymmetric thickening or both

rheumatic

commissural fusion with mitral valve stenosis

degenerative

thickening and increased echogenicity of the cusps (excluding the free edges) with reduced systolic opening

 

 

Aortic Valvular Calcifications on Echocardiography

Degree

Grade

none or minimal

none

1

small isolated spots (mild)

mild

2

multiple, large spots (moderate)

moderate

3

extensive thickening and calcification of the cusps

severe

4

 

Mitral annular calcifications defined as dense, highly reflective area at the base of the mitral valve leaflet.

 

increase in aortic-jet velocity in m/sec =

= ((aortic jet velocity in m/sec at first exam) – (aortic jet velocity in m/sec at second exam)) / (time in years between examinations)

 

where:

• The examinations are >= 6 months apart.

 

Risk factors for poor prognosis in patients with asymptomatic aortic stenosis:

(1) presence of moderate or severe valvular calcifications

(2) increase in mean aortic-jet velocity (>= 0.3 m per second per year)

 

Factors not found to be independent predictors:

(1) age

(2) sex

(3) coronary artery disease

(4) hypertension

(5) diabetes mellitus

(6) hypercholesterolemia

 


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