Certain findings may indicate a poor prognosis in patients with meningiomas.
With multivariate analysis of overall survival using Cox proportional hazard modeling, 4 parameters were found associated with poor survival.
Parameters
Risk Ratio with 95% Confidence Intervals
frank anaplasia in histologic appearance
3.629 (1.527 - 8.626)
subtotal resection (inability to totally resect)
excessive mitotic index, with >= 20 mitoses per 10 high power fields
3.594 (1.416 - 9.121)
nuclear atypia
3.467 (1.408 - 8.539)
from Table 4, page 2051.
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Specialty: Hematology Oncology, Surgery, general, Neurology
