Donadio et al used the plasma creatinine and body composition analysis by bioelectrical impedance analysis (BIA) to calculate a patient's creatinine clearance. The authors are from the University of Pisa.
Parameters:
(1) plasma creatinine in mg/dL
(2) body weight in kilograms
(3) 24-hour urine creatinine in mg estimated from fat free mass (FFM)
(4) 24-hour urine creatinine in mg estimated from body cell mass (BCM)
Male
Female
24 hour urine creatinine in mg based on FFM
25.6 mg per kg FFM +/- 3.8
22.5 mg per kg FFM +/- 3.8
24 hour urine creatinine in mg based on BCM
51.9 mg per kg BCM +/- 5.9
48.1 mg per kg BCM +/- 8.0
creatinine clearance by FFM =
= (24 hour urine creatinine in mg per kg FFM) * (FFM in kg) / ((plasma creatinine) / 100 * 1440)
creatinine clearance by FFM =
= (24 hour urine creatinine in mg per kg BCM) * (BCM in kg) / ((plasma creatinine) / 100 * 1440)
where:
• Division of plasma creatinine by 100 is to convert from mg per dL to mg per mL.
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