Fu et al evaluated the impact of thrombolytic parameters on 1-year mortality following percutaneous coronary intervention (PCI). The authors participated in the ASSENT-2 trial.
Parameters:
(1) time to treatment in hours
(2) percent resolution of ST elevation at 24 to 36 hours after fibrinolysis
Time to Treatment
Percent Resolution
1-Year Mortality Rate
< 2 hours
>= 70%
3.8%
30 to 69%
5.7%
0 to 29%
7.3%
2 to 4 hours
>= 70%
5.2%
30 to 69%
8.4%
0 to 29%
8.7%
> 4 hours
>= 70%
6.6%
30 to 69%
9.9%
0 to 29%
13%
where:
• 70-100% resolution in ST elevation indicates complete ST elevation resolution. 30-69% indicates partial resolution. Less than 30% indicates no resolution.
In Figure 7 the line for percent ST rsolution at 24 to 36 hours after fibrinolysis versus 1 year mortality rate:
1-year mortality rate in percent =
= (-0.05695 * (percent resolution)) + 11
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