Patient selection: child with primary immune thrombocytopenia (ITP), from 3 months to 16 years of age
The platelet count should be <= 20 * 10^-9/L.
Transient ITP is complete recovery with platelet count >= 100 * 10^9/L at 3 months after diagnosis.
Parameters:
(1) age in years
(2) platelet count in 10^9/L
(3) sex
(4) history of preceding infection
(5) history of preceding vaccination
(6) mucosal bleeding
(7) insidious disease onset
|
Parameter
|
Finding
|
Points
|
|
age
|
|
-0.03 * (years)
|
|
platelet count
|
|
-0.02 * (count)
|
|
sex
|
female
|
0
|
|
|
male
|
0.09
|
|
history of infection
|
no
|
0
|
|
|
yes
|
0.18
|
|
history of vaccination
|
no
|
0
|
|
|
yes
|
0.11
|
|
musocal bleeding
|
no
|
0
|
|
|
yes
|
0.17
|
|
insidious onset
|
no
|
0
|
|
|
yes
|
-1.15
|
X =
= SUM(values for all 11 parameters) + 1.11
probability of transient course =
= 1 / (1 + EXP((-1) * X))
probability of persistent disease =
= 1 - (probability of transient course)
