Schmidt et al reported a model for predicting the time course of childhood immune thrombocytopenia. The authors are from multiple institutions in The Netherlands.
Patient selection: child with primary immune thrombocytopenia (ITP), from 3 months to 16 years of age
The platelet count should be <= 20 * 10^-9/L.
Transient ITP is complete recovery with platelet count >= 100 * 10^9/L at 3 months after diagnosis.
(1) age in years
(2) platelet count in 10^9/L
(4) history of preceding infection
(5) history of preceding vaccination
(6) mucosal bleeding
(7) insidious disease onset
-0.03 * (years)
-0.02 * (count)
history of infection
history of vaccination
= SUM(values for all 11 parameters) + 1.11
probability of transient course =
= 1 / (1 + EXP((-1) * X))
probability of persistent disease =
= 1 - (probability of transient course)
To read more or access our algorithms and calculators, please log in or register.
Specialty: Hematology Oncology