Osterroos et al reported a score for predicting early mortality for a patient with acute promyelocytic leukemia. This can help to identify a patient who may require more aggressive management. The authors are from multople institutions in Sweden.
Patient selection: acute promyelocytic leukemia
Outcome: early death (death within 30 days)
Parameters:
(1) age in years
(2) WBC count in 10^9/L
(3) platelet count in 10^9/L
Parameter
Finding
Points
age in years
< 50 years
0
50 to 59 years
1
60 to 69 years
2
>= 70 years
3
WBC count
< 3 * 10^9/L
0
3 to 5 * 10^9/L
1
> 5 * 10^9/L
3
platelet count
>= 30 * 10^9/L
0
< 30 * 10^9/L
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
Total Score
Risk Group
Risk
0 to 2
low
< 10% (5 to 7%)
3 or 4
high risk
10 to 30% (20 to 25%)
5 to 7
very high risk
> 30% (36 to 51%)
Performance:
• The area under the ROC curve is 0.77.
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