Description

Osterroos et al reported a score for predicting early mortality for a patient with acute promyelocytic leukemia. This can help to identify a patient who may require more aggressive management. The authors are from multople institutions in Sweden.


Patient selection: acute promyelocytic leukemia

Outcome: early death (death within 30 days)

 

Parameters:

(1) age in years

(2) WBC count in 10^9/L

(3) platelet count in 10^9/L

 

Parameter

Finding

Points

age in years

< 50 years

0

 

50 to 59 years

1

 

60 to 69 years

2

 

>= 70 years

3

WBC count

< 3 * 10^9/L

0

 

3 to 5 * 10^9/L

1

 

> 5 * 10^9/L

3

platelet count

>= 30 * 10^9/L

0

 

< 30 * 10^9/L

1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 7

 

Total Score

Risk Group

Risk

0 to 2

low

< 10% (5 to 7%)

3 or 4

high risk

10 to 30% (20 to 25%)

5 to 7

very high risk

> 30% (36 to 51%)

 

Performance:

• The area under the ROC curve is 0.77.


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