Prediction Model of Meurs et al for Invasive Breast Cancer for a Woman with Ductal Carcinoma in Situ (DCIS) in a Breast Biopsy

Description

Meurs et al reported a model for predicting invasive breast cancer in a woman with ductal carcinoma in situ (DCIS) identified in a breast biopsy. This can help to guide management of the patient. The authors are from multiple institutions in The Netherlands.

Patient selection: DCIS seen in a breast biopsy

Parameters:

(1) detection mode (screen, otherwise)

(2) palpable

(3) BI-RADS 3, 4 or 5

(4) DCIS grade

(5) suspected invasive component at biopsy

Parameter	Finding	Points
detection mode	by screening	0
	other than screening	0.1555
palpable	no	0
	yes	0.7985
BI-RADS	3	-0.1464
	4	0
	5	0.8589
DCIS grade	low	0
	intermediate	0.3111
	high	0.3571
suspected invasive component	no	0
	yes	1.3445

value of X =

= SUM(points for all 5 parameters) - 2.1131

probability of invasive breast cancer =

= 1 / (1 + EXP((-1) * X))

Performance:

• The area under the ROC curve is 0.66.

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Prediction Model of Meurs et al for Invasive Breast Cancer for a Woman with Ductal Carcinoma in Situ (DCIS) in a Breast Biopsy

Description

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