Jiang et al reported a model for predicting the risk of preeclampsia in a pregnant Chinese woman with systemic lupus erythematosus (SLE). The score can help to identify a woman who may need more aggressive management. The authors are from Shanghai Jiao Tong University and affiliated institutions.
Patient selection: pregnant Chinese woman with systemic lupus erythematosus (SLE)
Parameters:
(1) prepregnancy hypertension
(2) mean arterial pressure in mm Hg
(3) hematologic disorder
(4) IgM anti-cardiolipin antibodies
(5) serum albumin in g/L
(6) serum uric acid in µmol/L
(7) 24-hour urine protein in grams per day
Parameter
Finding
Points
prepregnancy hypertension
no
0
yes
2
mean arterial pressure
< 96,5 mm Hg
0
>= 96.5 mm Hg
3
hematologic disorder
no
0
yes
1
IgM anti-cardiolipin Ab
no
0
yes
2
serum albumin
< 31.5 g/L
1
>= 31.5 g/L
0
serum uric acid
< 30.3 µmol/L
0
>= 30.3 µmol/L
1
24-hour urine protein
< 0.286 g per day
0
>= 0.286 g per day
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 11
• A score > 4 indicates high risk and a score <= 4 indicates low risk for preeclampsia.
Perforamnce:
• The area under the ROC curve is reported as 0.97.
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