Crapo and Morris (1981)
ages: 15-91 years
diffusing capacity per liter of lung volume in males =
= 7.08 - (0.034 * (age in years))
diffusing capacity per liter of lung volume in nonsmoking males =
= 6.93 - (0.033 * (age in years))
diffusing capacity per liter of lung volume in females =
= 6.58 - (0.025 * (age in years))
diffusing capacity per liter of lung volume in nonsmoking females =
= 6.94 - (0.028 * (age in years))
where:
• The diffusing capacity is reported in mL of CO (at STPD) per minute per mm Hg.
• Although the authors list equations corrected for hemoglobin in Table 2 (page 186), patient hemoglobin is not a factor. I would use the general equation to estimate the diffusing capacity, then use the equations in 08.03.03 to adjust.
• The study was done in Utah at an altitude of 1400 meters, while the other below were done close to sea level.
Teculescu (1970) for Nonsmokers
ages: 19-67 years
diffusing capacity per liter of lung volume in males =
= 8.50 - (0.051 * (age in years))
Salorinne (1976) for Nonsmokers
ages: 20-69 years
diffusing capacity per liter of lung volume in males =
= 12.50 - (0.029 * (age in years)) - (0.0353 * (height in cm))
diffusing capacity per liter of lung volume in females =
= 12.39 - (0.0131 * (age in years)) - (0.0396 * (height in cm))
Frans (1975) for Nonsmokers
ages: mean 38.5, standard deviation 11.7 years
diffusing capacity per liter of lung volume in males =
= 6.18 - (0.0296 * (age in years)) + (0.000157 * ((age in years)^2))
Hall (1979) for Nonsmokers
ages: 27-74 years
diffusing capacity per liter of lung volume in females =
= 4.46 - (0.021 * (age in years)) + (870 * (weight in kilograms) / ((height in cm)^2))
