Predicting Outcome for a Patient Hospitalized for Heart Failure Based on the Discharge BNP

Description

Di Somma et al evaluated Italian patients admitted to the hospital with acute heart failure. They used BNP levels to help to identify patients who may require more aggressive management over time. The authors are from multiple hospitals in Italy and the San Diego VA Hospital.

Patient selection: admission for acute heart failure

Adverse outcomes:

(1) readmission for heart failure

(2) death from cardiovascular event

Parameters:

(1) admission BNP in pg/mL

(2) discharge BNP in pg/mL

percent reduction in BNP between admission and discharge =

= ((admission BNP) - (discharge BNP) / (admission BNP) * 100%

Percent Reduction in BNP	Discharge BNP	Odds Ratio for Adverse Outcome
> 46%	< 300 pg/mL	1
> 46%	>= 300 pg/mL	2.1
<= 46%	< 300 pg/mL	7.8
<= 46%	>= 300 pg/mL	9.6

where:

• The Triage BNP test was used in the study.

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Description

Specialty

ICD-10