Description

Van den Boogaard et al reported the PRE-DELIRIC (PREdiction of DELIRium in ICu patients) model for predicting delirium in an intensive care unit (ICU) patient. This can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in the Netherlands.


Patient selection: ICU patient >= 18 years of age

 

Parameters:

(1) age in years

(2) APACHE-II score (timing not stated)

(3) coma status

(4) hospital service

(5) infection

(6) metabolic acidosis

(7) 24 hour morphine use (or equivalent)

(8) use of sedatives

(9) serum urea concentration in mmol/L

(10) urgent admission

 

Parameter

Finding

Points

age in years

 

0.04 * (age)

APACHE II score

 

0.06 * (APACHE II)

coma

none

0

 

drug-induced

0.55

 

miscellaneous

2.70

 

combination

2.84

hospital service

surgical

0

 

medical

0.31

 

trauma

1.13

 

neurology or neurosurgical

1.38

infection

no

0

 

yes

1.05

metabolic acidosis

no

0

 

yes

0.29

24 hour morphine use

none

0

 

0.01 to 7.1 mg

0.41

 

7.2 to 18.6

0.13

 

> 18.6

0.51

use of sedatives

no

0

 

yes

1.39

serum urea

 

0.03 * (urea)

urgent admission

no

0

 

yes

0.40

 

X =

= SUM(points for all of the parameters) - 6.31

 

probability of delirium =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.85.


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