A patient may develop a nongranulomatous uveitis following an infection with Group A Streptococcus (Streptococcus pyogenes).


Clinical findings:

(1) recent infection with Group A Streptococcus

(2) bilateral ocular involvement

(3) reduced visual acuity


The patient may develop:

(1) anterior uveitis

(2) variable involvement of the posterior segment (vitritis, choroiditis, swelling of the optic disc, focal retinitis)

(3) panuveitis


Other complications associated with the poststreptococcal syndrome may include:

(1) reactive arthritis

(2) erythema nodosum

(3) glomerulonephritis


Making the diagnosis:

(1) exclusion of other causes

(2) serologic evidence of a recent streptococcal infection (anti-streptococcal lysine O/ASO, anti-deoxyribonuclease B)

(3) recurrence with subsequent episodes of Group A streptococcal infections


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