Bennett et al reported hyperlactatemia and other predictors for in-hospital mortality for a patient with Type A aortic dissection undergoing surgery. The authors are from Vanderbilt University.

Patient selection: acute type A aortic dissection


Risk factors for in-hospital mortality:

(1) elevated serum lactic acid concentration, >= 6.0 mmol/L (OR 1.5)

(2) effusion (OR 4.8)

(3) neurologic change (OR 5.3)

(4) severe aortic regurgitation (6.8)


The severity of the malperfusion syndrome (cerebral, cardiac, visceral) also impact outcomes.

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