Description

Henoch-Schonlein purpura associated with Group A streptococcal infection is an uncommon condition. It is also the probable cause of Mozart's death.


Clinical features:

(1) recent evidence of infection with Group A Streptococcus infection, with or without rheumatic fever

(2) onset of Hemoch-Schonlein purpura, with one or more of the following:

(2a) skin rash

(2b) glomerulonephritis with IgA mesangial deposits and/or nephritis

(2c) myocarditis

(2d) neurologic findings

(2e) arthralgias/arthritis

 

Variable findings:

(1) hypocomplementemia may be present.

(2) significant proteinuria including nephrotic syndrome


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