The Post-Cholecystectomy Syndrome (PCS) refers to continuation of signs and symptoms following a cholecystectomy.


Patient selection: post-cholecystectomy


Clinical findings may include:

(1) persistent upper abdominal pain

(2) dyspepsia

(3) vomiting

(4) jaundice


The onset of symptoms may be early or late, which impacts the choices in the differential diagnosis.


Differential diagnosis:

(1) stones in the liver or common bile duct (choledocholithiasis)

(2) cystic duct or gallbladder remnant syndrome

(3) bile leakage (other than at the cystic duct remnant)

(4) biliary dyskinesia with or without sphincter of Oddi dysfunction

(5) bile duct injury, stricture or ligature

(6) surgical site infection

(7) other surgical complication (damage to artery or vein, other)

(8) other pathology unrelated to the gallbladder or cholecystectomy


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