Tamayo et al reported the Post Cardiac Surgery (POCAS) prognostic score for predicting operative mortality for a patient undergoing cardiac surgery. The authors are from the Hospital Universitario de La Princesa in Madrid.
Patient selection: cardiac surgery with cardiopulmonary bypass
Rate on in-hospital mortality: 9%
Outcome: 90-day in-hospital mortality
Parameters at admission to ICU after surgery:
(1) mean arterial pressure (MAP), within 30 minutes of ICU admission and when patient hemodynamically stable
(2) serum bicarbonate in mmol/L (mEq/L)
(3) serum lactate ratio in mmol/L
(4) INR
Parameter |
Finding |
Points |
lactate |
< 16 mmol/L |
3 |
|
16 to 24.9 |
4 |
|
25 to 34.9 |
6 |
|
35 to 52.9 |
9 |
|
53 to 79 |
14 |
|
> 79 mmol/L |
21 |
mean arterial pressure |
> 75 mm Hg |
35 |
|
69 to 75 |
41 |
|
61 to 68 |
46 |
|
60 |
50 |
|
45 to 59 |
58 |
|
< 45 mm Hg |
75 |
INR |
< 1.31 |
12 |
|
1.31 to 1.52 |
14 |
|
1.53 to 1.94 |
16 |
|
1.95 to 2.65 |
20 |
|
> 2.65 |
30 |
bicarbonate |
> 27.4 mmol/L |
14 |
|
25.7 to 27.4 |
1511 |
|
24.1 to 25.6 |
16 |
|
22.8 to 24 |
17 |
|
20.4 to 22.7 |
18 |
|
14.6 to 20.3 |
22 |
|
< 14.6 mmol/L |
35 |
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 64
• maximum score: 161
• The higher the score the greater the risk of mortality.
If risk categories are combined, the following groups are identified.
Total Score |
Risk Group |
90-Day In-Hospital Mortality |
64 to 90 |
low |
2.3% |
91 to 105 |
medium |
16% |
106 to 128 |
high |
56% |
> 128 |
very high |
95% |
If the low and medium risk groups are not combined, the following rates are seen.
Total Score |
Mortality |
64 to 74 |
0.4% |
75 to 81 |
1.5% |
82 to 90 |
6% |
91 to 100 |
11% |
101 to 105 |
28% |
value of X =
= (0.113 * (score)) - 12.671
probability of in-hospital mortality =
= 1/(1+EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.90.
• The mean arterial pressure had an AROC of 0.86.
Specialty: Cardiology, Surgery, general