As with polypharmacy too many herbal or alternative remedies may have unwanted side effects.

A person may become exposed to multiple herbs in 2 ways:

(1) taking a polyherbal remedy

(2) taking multiple separate herbal remedies


Factors associated with adverse side effects when taking multiple herbal remedies:

(1) total number of herbs exposed to

(2) number taken at high dose

(3) frequency of dosing

(4) concurrent medications

(5) comorbid illness (renal failure, liver disease, etc)

(6) adulteration

(7) drug-herb-food interactions

(8) allergies

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