PLATO = platelet inhibition and patients outcome
Patient selection: antiplatelet therapy
Major life-threatening bleeding:
(1) fatal
(2) intracranial
(3) intrapericardial with cardiac tamponade
(4) hypovolemic shock or severe hypotension requiring pressors or surgery
(5) hemoglobin drop >= 5 g/dL
(6) transfusion >= 4 units of blood
Other major bleeding:
(1) significant disability (intraocular bleeding with vision loss, other)
(2) hemoglobin drop 3.00 to 4.99 g/dL
(3) transfusion >= 2 to < 4 units of blood
Minor bleeding:
(1) any other bleeding not designated major
