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Plasma Drug Concentration for a Bolus Infusion Regimen

Specialty:

Toxicology
Emergency Medicine
Critical Care

Objective:

ICD-10:

Description:

After a bolus (rapid) intravenous infusion of drug, the plasma concentration usually reaches a maximum concentration quickly, after which it declines. For many drugs this occurs as a first order process. The primary differences from oral dosing are that there is no absorption phase and the total dose is delivered.

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