The ratio of amyloid beta-42 to amyloid beta-40 is associated with the patient's status on amyloid PET scan.
Parameters:
(1) plasma concentration of amyloid beta 42 in pg/mL
(2) plasma concentration of amyloid beta 40 in pg/mL
ratio =
= (amyloid beta 42) / (amyloid beta 40)
Interpretation:
• A reduced ratio is seen in patients with a positive amyloid PET scan.
• The results need to be interpreted along with the patient's apolipoprotein (APOE) epsilon status.
