Placental transmogrification is a rare condition seen in histologic sections of the lung, most often seen in emphysematous lung.
Synonym: placentoid bullous lesion of the lung
Placental transmogrification involves formation of villous-like structures projecting into dilated alveoli. These resemble placental villi when observed at low power.
The structures show a fibrovascular core with edema and patchy chronic inflammation.
Conditions associated with placental transmogrification:
(1) severe emphysema
(2) congenital giant bullous emphysema
(3) Swyer-James-MacLeod syndrome
(4) fibrochondromatous hamartomas of the lung
(5) pulmonary lipomatosis
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