Placental transmogrification is a rare condition seen in histologic sections of the lung, most often seen in emphysematous lung.


Synonym: placentoid bullous lesion of the lung


Placental transmogrification involves formation of villous-like structures projecting into dilated alveoli. These resemble placental villi when observed at low power.


The structures show a fibrovascular core with edema and patchy chronic inflammation.


Conditions associated with placental transmogrification:

(1) severe emphysema

(2) congenital giant bullous emphysema

(3) Swyer-James-MacLeod syndrome

(4) fibrochondromatous hamartomas of the lung

(5) pulmonary lipomatosis


To read more or access our algorithms and calculators, please log in or register.