Mehrotra et al reported the PILE score for older adults with obstructive airway disease. This can help to identify a patient who may benefit from more aggressive management. The authors are from the University of Tennessee, National Institute on Aging, University of Pittsburgh and Wake Forest University.
Patient selection: adult 70-79 years of age, with FEV1 >= 30% of predicted
Obstructive airway disease was defined as a reduced FEV1/FVC ratio based on normalized values from NHANESIII.
Parameters:
(1) percent of the predicted FEV1 (P)
(2) interleukin-6 (IL) in pg/mL
(3) knee extensor strength (torque) in Newton•meters and sex (E)
Parameter
Finding
Points
FEV1 as percent of predicted
> 80%
0
51 to 80%
1
30 to 50%
2
interleukin 6
0.45 to 1.39 pg/mL
0
1.40 to 1.85 pg/mL
1
1.86 to 2.41 pg/mL
2
2.42 to 3.77 pg/mL
3
3.78 to 13.25 pg/mL
4
knee extensor strength
131.0 to 221.1 and male
0
115.7 to 130.9 and male
1
99.3 to 113.5 and male
2
83.4 to 98.9 and male
3
19.5 to 81.6 and male
4
86.4 to 137.7 and female
0
72.5 to 84.7 and female
1
62.4 to 72.3 and female
2
51.3 to 61.4 and female
3
12.9 to 49.9 and female
4
where:
• There are gaps in the knee extensor strength ranges.
Interpretation:
• minimum score: 0
• maximum score: 10
• The higher the score the greater the mortality rate.
PILE Score
6.1 Year Mortality
0
NA
1
0%
2
13%
3
25%
4
22%
5
22%
6
37%
7
50%
8
63%
9
58%
10
80%
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