Pheochromocytoma in Children | Medical Algorithm

Kohane et al listed clinical signs and symptoms that may be seen in a child with a pheochromocytoma. The authors are from Harvard Medical School.

Clinical signs and symptoms:

(1) hypertension

(2) orthostatic hypotension

(3) tachycardia

(4) dysrhythmias

(5) cardiomyopathy with heart failure

(6) acrocyanosis

(7) blurred vision and papilledema

(8) headache

(9) emotional lability

(10) hypertensive encephalopathy

(11) tremor

(12) polycythemia

(13) nausea and vomiting

(14) constipation

(15) weight loss

(16) growth failure

(17) polydipsia

(18) polyuria

(19) enuresis

(20) sweating (diaphoresis)

(21) unexplained hyperglycemia

where:

• The classic triad of pheochromocytoma in an adult is headache, palpitations and flushing.

Differential diagnosis:

(1) thyrotoxicosis

(2) carcinoid tumor

(3) cocaine or drug abuse

(4) exposure to an adrenergic agent

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Clinical Symptoms for Pheochromocytoma in Pediatric Patient