A patient with a pheochromocytoma may become symptomatic when certain events trigger release of catecholamines from the tumor.


Physical events:

(1) exercise or exertion

(2) bending over

(3) pressure applied to the abdomen or abdominal palpation

(4) defecation and/or urination

(5) straining


Biochemical release or injection:

(1) histamine

(2) glucagon

(3) ACTH



(1) tricyclic antidepressants

(2) phenothiazines

(3) guanethidine

(4) tyramine

(5) naloxone

(6) metoclopramide

(7) droperidol

(8) cytotoxic drugs


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