Rhabdomyolysis may occur in the perioperative period. It often occurs unexpectedly and it requires prompt diagnosis to avoid complications..


Risk factors for rhabdomyolysis:

(1) prolonged surgery (several hours)

(2) certain positions (lithotomy, lateral decubitis)

(3) hard operating table surface

(4) obesity

(5) other chronic comorbid conditions


The rhabdomyolysis may be associated with a compartment syndrome.


A delay in diagnosis can result in myoglobinuria-related acute renal failure. Early and prompt diuresis and alkalinization of the urine can reduce this risk.


The diagnosis requires exclusion of other diagnoses (myopathy, drug reaction, hemolytic transfusion reaction).


To read more or access our algorithms and calculators, please log in or register.