Perinatal, Surgical and Clinical Model (Full Model) of Seetharamaiah et al for Predicting Survival in an Infant with Congenital Diaphragmatic Hernia Requiring ECMO
Seetharamaiah et al developed models for predicting survival for infants with congenital diaphragmatic hernia who required extracorporeal membrane oxygenation (ECMO). One of these models is based on all available information (perinatal, surgical, clinical data). The authors are from the University of Michigan and Mott Children's Hospital in Ann Arbor.
Parameters:
(1) birth weight in kilograms
(2) gestational age at birth in weeks
(3) 5 minute Apgar score
(4) cormorbid cardiac anomaly
(5) need for second course of ECMO therapy
(6) patch repair of diaphragm
(7) race
(8) number of days on ECMO
Parameter
Finding
Points
birth weight
>= 3 kg
0
< 3 kg
-0.43
gestational age
>= 38 weeks
0
< 38 weeks
-0.44
5 minute Apgar score
>= 7
0
< 7
-0.47
cardiac anomaly
none, mild or moderate
0
severe
-0.95
need for second course ECMO
no
0
yes
-0.91
patch repair of diaphragm
no
0
yes
-0.59
race
non-Caucasian
0
Caucasian
0.34
X =
= SUM(points for the first 7 parameters) - 6.8 + (8.08 / SQRT(days on ECMO)) + (8.92 * LN(days on ECMO) / SQRT(days on ECMO))
probability of survival =
= 1 / (1 + EXP((-1) * X))
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