Sadozai et al reported the POPI tool (Pediatrics: Omission of Prescriptions and Inappropriate Prescriptions) for problematic therapies for pediatric patient. Categories included respiratory and gastrointestinal tract therapeutics. The authors are from multiple institutions in Paris.
Patient selection: pediatric patients
Categories:
(1) asthma
(2) cough
(3) bronchiolitis
(4) anorexia
(5) nausea and vomiting
(6) GERD
(7) diarrhea
Inappropriate prescriptions:
(1) metoclopramide or domperidone for nausea or vomiting
(2) oral administration of an intravenous proton pump inhibitor (PPI) for GERD
(3) gastric antisecretory drugs to treat GERD, dyspepsia or crying in an infant
(4) combined use of PPI and NSAIDs in a patient without risk factors
(5) use of H2 antihistamines for a long period
(6) oral rehydration solution in the absence of dehydration
(7) loperamide for diarrhea in a child less than 3 years of age or for invasive diarrhea
(8) intestinal antiseptics for diarrhea
(9) use of Sacchararomycesboulardii in powder or opened capsule in a child with a central venous catheter or an immunodeficiency
(10) mucolytic drugs, muokinetic drugs or helicidine for cough in a child less than 2 years of age
(11) beta-2 agonists or corticosteroids to treat an infant's first case of bronchiolitis
(12) treating bronchiolitis with H1-antagonists, cough suppressants, mucolytic drugs or ribavirin
(13) treating bronchiolitis with antibiotics in the absence of signs indicating a bacterial infection
(14) ketotifen or other H1-antagonists for a child with asthma
(15) sodium cromoglycate for asthma
(16) cough suppressant for asthma
Therapeutic omissions:
(1) oral rehydration solution for diarrhea
(2) use of 0.9% sodium chloride to relieve nasal congestion in an infant with bronchiolitis
(3) asthma inhaler appropriate for age
(4) preventative treatment in the case of persistent asthma
