Patient selection: adolescent girl with polycystic ovary disease (POS)
Parameters:
(1) BMI percentile, from 89 to 100
(2) waist circumference in cm, from 80 to 130
(3) serum ALT in IU/L, from 10 to 100
(4) SHBG (sex hormone binding globulin) in nmol/L, from 0 to 80
points for BMI percentile =
= 402.72 - (4.027 * (percentile))
points for waist circumference =
= (0.72 * (circumference)) - 57.6
points for serum ALT =
= (1.11 * (ALT)) - 11.11
points for SHBG =
= 75.6 - (0.945 * (SHBG))
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 256.5
• The higher the score the greater the risk.
|
Total Score
|
Risk Group
|
PCOS-HS
|
|
<= 90
|
low
|
<= 0.15
|
|
91 to 109
|
intermediate
|
0.16 to 0.43
|
|
>= 110
|
high
|
>= 0.44
|
Performance:
• The area under the ROC curve was 0.81.
