Lane et al developed a nomogram for predicting the likelihood of an aggressive renal carcinoma in a tumor removed by partial nephrectomy. This can help to identify a patient who may benefit from more aggressive management. The authors are from the Glickman Urological Institute and the Cleveland Clinic in Cleveland, Ohio.
Patient selection: solid enhancing renal tumor 7 cm or less in diameter in a patient from 20 to 90 years of age
Parameters:
(1) age
(2) gender
(3) diameter of the tumor in cm
(4) local symptoms at diagnosis
(5) history of smoking
points for tumor diameter =
= (6.4 * (diameter in cm)) - 3.2
points for age =
= (1.4286 * (age in years)) - 28.57
Parameter |
Finding |
Points |
gender |
female |
0 |
|
male |
7.8 |
local symptoms at diagnosis |
yes |
0 |
|
no |
3 |
history of smoking |
no |
0 |
|
yes |
8.3 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 160
• The higher the score the greater the likelihood of the tumor being aggressive.
Probability |
Total Score |
< 15% |
< 27 points |
15 to 50% |
(0.000818 * ((points)^2)) + (0.1488 * (points)) + 10.25 |
> 50% |
> 148 points |
Purpose: To predict the probability that a renal tumor <= 7 cm in diameter removed by partial nephrectomy is an aggressive carcinoma based on the model of Lane et al.
Specialty: Hematology Oncology, Surgery, general, Nephrology
Objective: risk factors, disease progression
ICD-10: C64, C65,