Paraneoplastic Limbic Encephalitis

Are you evaluating a patient for the presence of paraneoplastic limbic encephalitis?

Yes

Number of months between onset of the neurologic syndrome and the diagnosis of cancer

months

Has the patient shown?

• personality changes including disinhibition?

Yes

• irritability?

Yes

• depression, hallucinations, or other psychiatric disturbances?

Yes

• seizures?

Yes

• short term memory loss ?

Yes

• disorientation to space and time?

Yes

• dementia?

Yes

Does the patient have evidence of?

• brain metastases?

Yes

• toxic or metabolic encephalopathy?

Yes

• viral encephalitis?

Yes

• cerebrovascular disease?

Yes

Do laboratory or imaging studies show?

• chronic inflammation in the CSF without malignant cells?

Yes

• temporal lobe abnormalities on MRI scans?

Yes

• epileptic activity in the temporal lobes in the EEG?

Yes

Select the appropriate answer to indicate antibody specificity identified

Antibodies in serum and/or CSF

Histopathologic findings

Please fill out required fields.

Data complete?

Evaluation appropriate?

Is the timing of symptom onset relative to tumor diagnosis appropriate?

Number of clinical features present

Number of exclusionary findings

Number of diagnostic tests supporting the diagnosis

Does the patient have paraneoplastic limbic encephalopathy?

Does the antibody found suggest a particular type of tumor?

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Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10

Purpose: To evaluate a patient for clinical findings associated with paraneoplastic limbic encephalitis (PLE).

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10