Parainfectious rhabdomyolysis refers to rhabdomyolysis during or after an infection.
Infections that may trigger rhabdomyolysis:
(1) sepsis
(2) toxic shock syndrome
(3) tetanus
(4) Rocky Mountain Spotted Fever (RMSF)
(5) legionellosis
(6) infectious mononucleosis
(7) trichinosis
(8) virus with influenza-like illness
Clinical findings:
(1) red-brown or cola colored urine
(2) normal to red-brown plasma
(3) oliguria or anuria
(4) mylagia or severe muscle pain
(5) muscle tenderness and/or swelling
(6) muscle weakness
(7) hypotension
Recurrent episodes raise the possibility of one of the following:
(1) congenital cataracts, facial dysmorphism, neuropathy syndrome (CCFDNS)
(2) immunodeficiency
(3) an underlying myopathy
In patients with CCFDNS the recovery from an episode of rhabdomyolysis may take months. Recurrent episodes can result in functional impairment made worse by the accompanying neuropathy.
Diagnosis of parainfectious rhabdomyolysis requires:
(1) documentation of infection just before or during the onset of muscle damage
(2) exclusion of other causes
Specialty: Surgery, orthopedic, Nephrology, Clinical Laboratory