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Paracetamol / Acetaminophen-Induced Acute Liver Failure | Criteria for Liver Transplantation

Purpose:

To determine if a person with paracetamol-induced liver failure should undergo liver transplantation using the modified King's College Hospital criteria.

Specialty:

Gastroenterology
General Surgery

Objective:

laboratory tests, other testing, severity, prognosis, stage, selection

ICD-10:

T39.1, K72.0

Description:

Bernai et al modified the King's College Hospital (KCH) criteria for identifying a patient with poor prognosis following paracetamol (acetaminophen)-induced acute liver failure. This involves the addition of arterial lactate measurements during the initial fluid resuscitation. A patient meeting these criteria should be considered for liver transplantation. The authors are from King's College and St Thomas's Hospitals in London.

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