Chow et al developed a model for predicting survival by a cancer patient who is receiving palliative radiotherapy. The authors are from Princess Margaret Hospital and the University of Toronto in Canada.
Prognostic scores:
(1) simple sum of risk factors
(2) survival prediction score (SPS)
Parameters:
(1) type of cancer
(2) sites of metastases
(3) Karnofsky Performance Scale (KPS)
(4) fatigue score on a scale of 0 to 10
(5) decreased appetite score on scale of 0 to 10
(6) shortness of breath score on a scale of 0 to 10
|
Parameter |
Finding |
Points |
|
type of cancer |
breast |
0 |
|
|
non-breast |
1 |
|
sites of metastases |
bone only |
0 |
|
|
other than bone only |
1 |
|
KPS |
> 50 |
0 |
|
|
<= 50 |
1 |
|
fatigue |
none or mild (0 to 3) |
0 |
|
|
moderate to severe (score 4 - 10) |
1 |
|
decreased appetite |
none to moderate (0 to 7) |
0 |
|
|
severe (8 to 10) |
1 |
|
shortness of breath |
none (score 0) |
0 |
|
|
mild to severe (1 to 10) |
1 |
simple score =
= SUM(points for all 6 parameters)
|
Parameter |
Finding |
Points |
|
type of cancer |
breast |
0 |
|
|
prostate |
5 |
|
|
lung |
6 |
|
|
other |
7 |
|
sites of metastases |
bone only |
0 |
|
|
other than bone only |
6 |
|
KPS |
> 50 |
0 |
|
|
<= 50 |
6 |
|
fatigue |
none or mild (0 to 3) |
0 |
|
|
moderate (4 to 7) |
4 |
|
|
severe (8 to 10) |
5 |
|
decreased appetite |
none to moderate (0 to 7) |
0 |
|
|
severe (8 to 10) |
4 |
|
shortness of breath |
none (score 0) |
0 |
|
|
mild (1 to 3) |
2 |
|
|
moderate to severe (4 to 10) |
4 |
survival prediction score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum scores: 0
• maximum simple score: 6
• maximum SPS: 32
• The higher the scores the worse the survival
|
Simple Score |
SPS |
Prognostic Group |
|
0 to 3 |
0 to 13 |
fair (A) |
|
4 |
14 to 19 |
guarded (B) |
|
5 or 6 |
20 to 32 |
poor (C) |
|
Prognostic Group |
Simple Score 52 Week Survival |
SPS 52 Week Survival |
|
fair (A) |
53% |
53% |
|
guarded (B) |
28% |
19% |
|
poor (C) |
10% |
5% |
Purpose: To evaluate survival in a patient with metastatic cancer who is receiving palliative radiotherapy using the scores of Chow et al.
Specialty: Hematology Oncology, Surgery, general
Objective: severity, prognosis, stage, end-of-life, palliative care
ICD-10: Z51.5,
