Papatheodoridis et al reported the PAGE-B score to predict the risk of developing hepatocellular carcinoma (HCC) in a Caucasian patient with chronic hepatitis B who is receiving antiviral therapy. The authors are from multiple institutions in Europe and Canada.
Patient selection: chronic hepatitis B (HBV), age >= 16 years, on antiviral therapy
Parameters:
(1) age in years (A), >= 16 years
(2) sex or gender (GE)
(3) platelet count per microliter (P)
Parameter
Finding
Points
age in years
16 to 29 years
0
30 to 39 years
2
40 to 49 years
4
50 to 59 years
6
60 to 69 years
8
>= 70 years
10
sex
female
0
male
6
platelet count
>= 200,000 per µL
0
100,000 to 199,999 per µL
6
< 100,000 per µL
9
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 25
• The higher the score the greater the risk of hepatocellular carcinoma.
