Noer et al developed a comorbidity score for women with ovarian cancer. This can help to identify a patient who may benefit from more aggressive maangement. The authors are from the University of Copenhagen, the Danish Cancer Society and Herlev University Hospital in Denmark.
Patient selection: ovarian cancer, age >= 16 years
Outcome: overall survival
Parameters:
(1) age in years
(2) arteriosclerotic heart disease
(3) hypertension
(4) chronic obstructive pulmonary disease (COPD)
(5) diabetes mellitus
(6) dementia
Parameters
Finding
Points
arteriosclerotic heart disease
absent
0
present
0.46
hypertension
absent
0
present
-0.29
COPD
absent
0
present
0.56
diabetes mellitus
absent
0
present
0.40
dementia
absent
0
present
0.81
total score =
= SUM(points for all 5 comorbid conditions)
Interpretation:
• minimum score: -0.29
• maximum score: 2.23
• The higher the score the greater the risk.
Age
Low Risk
Moderate Risk
High Risk
16 to 44 years
< 1.21
1.21 to 3.63
>= 3.64
45 to 54 years
< 0.28
0.28 to 1.73
>= 1.74
55 to 64 years
< -0.22
-0.22 to 1.11
>= 1.12
65 to 74 years
< -0.57
-0.57 to 0.52
>= 0.53
>= 75 years
< - 1.20
-1.20 to -0.30
>= -0.31
where:
• Certain cells cannot be met with score: high risk for 16 to 44 years, low risk for >= 65 years, moderate risk for >= 75 years.
• Low risk is associated with 75% chance of surviving > 24 months. Moderate risk with 75% chance of surviving 6.1 to 24 months. High risk with 75% chance of surviving <= 6 months.
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