A woman with a hereditary coagulation defect such as von Willebrand's disease may present with major bleeding from the ovary.


Clinical features:

(1) familial or personal history of a bleeding disorder

(2) major intrapelvic bleeding shown to be arising from the ovary, with or without a structural lesion (such as a hemorrhagic corpus luteum)

(3) exclusion of other explanations, including anticoagulation therapy


A woman with excessive bleeding from the ovary should be evaluated for a congenital bleeding disorder if no other explanation is identified.


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