A patient who abuses methamphetamine or cocaine may develop osteonecrosis of the jaw.
(1) onset of osteonecrosis of the jaw
(2) history of methamphetamine and/or cocaine
(3) exclusion of other diagnoses
(4) other signs of drug abuse including poor oral health
(1) vasoconstriction with ischemia
(2) exposure to red or white phosphorus (vapors or drug contaminant from methamphetamine production)
(3) self-extraction of teeth
(1) osteomyelitis of the jaw
(2) other causes of medication-related osteonecrosis of the jaw (MRONJ)
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