Takenaka et al reported a comorbidity score for patients with squamous cell carcinoma of the head and neck. This correlates with overall survival. The authors are from Osaka University.
Patient selection: Japanese adults with head and neck cancer
Outcome: 5-year overall survival
Parameters:
(1) lung cancer
(2) synchronous esophageal cancer
(3) gastric cancer
(4) metachronous head and neck cancer
(5) metachronous esophageal cancer
(6) connective tissue disease
(7) dementia
Parameter
Finding
Points
lung cancer
absent
0
present
3
synchronous esophageal cancer
absent
0
present
1
gastric cancer
absent
0
present
1
metachronous head and neck cancer
absent
0
present
1
metachronous esophageal cancer
absent
0
present
1
connective tissue disease
absent
0
present
3
dementia
absent
0
present
3
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 13
• The higher the score the greater the comorbidity and the worse the survival.
Total Score
Overall 5-Year Survival
0
62%
1
64%
>= 2
38%
Performance:
• The area under the ROC curve is 0.75.
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