Oral Verruciform Xanthoma (OVX) is a benign lesion of the oral mucosa.
Clinical appearance:
(1) “normal”, pale, yellowish or reddish
(2) rough surface with variable hyperkeratosis
(3) sessile or pedunculated
(4) diameter up to 1.5 cm
Location:
(1) palate
(2) tongue
(3) buccal mucosa
(4) gingiva
The diagnosis is made by histologic exam of a biopsy or resected specimen.
Histologic features:
(1) large number of xanthoma cells in the submucosa (PAS positive, CD68 positive)
(2) exclusion of malignancy or alternative diagnosis
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Specialty: Otolaryngology
