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Oral Desensitization Protocol of Gluckstein and Ruskin for a Patient with a Sensitivity Reaction to Trimethoprim-Sulfamethoxazole

Specialty:

Infectious Diseases
Clinical Pharmacology & Toxicology

Objective:

ICD-10:

Description:

Gluckstein and Ruskin developed a protocol for rapid oral desensitization for patients with a history of sensitivity to trimethoprim-sulfamethoxazole (TMP-SMZ). It was developed for patients with AIDS who required prophylaxis against pneumocystosis, but can be used for other patients in whom the benefit justifies the risk. The authors are from the Kaiser Permanente Medical Center in Los Angeles.

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