A patient born with congenital Zika infection may have a number of ophthalmologic changes as a result. An ophthalmologic exam should be performed if congenital Zika infection is suspected.

Microcephaly was present in the infants.


Ophthalmologic findings are bilateral.


Characteristic triad:

(1) epiphora (excessive tearing)

(2) photophobia

(3) blepharospasm


Ophthalmologic changes may include:

(1) macular abnormalities (pigment mottling, lacunar maculopathy)

(2) increased intra-ocular pressure with possibility of congenital glaucoma

(3) corneal clouding

(4) buphthalmos (enlargement of the globe)

(5) optic nerve findings (hypoplasia with double ring sign, pallor, increased cup-to-disc ratio)

(6) chorioretinal atrophy and scarring

To read more or access our algorithms and calculators, please log in or register.