Ofuji papuloerythroderma is a rare paraneoplastic skin disorder first described in Japan.


Clinical and laboratory features:

(1) disseminated erythematous (red-brown), flat-topped papules

(2) sparing of skin folds (deck-chair sign): axillae, inguinal regions, poplital fossae, antecubital fossae, abdominal skin folds

(3) pruritus

(4) eosinophilia


The malignancy most often associated with Ofuji papuloerythroderma is a T-cell leukemia or lymphoma.


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