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Ocular Changes in a Patient with Juvenile Paget Disease

Specialty:

Neurology, Psychiatry, Ophthalmology & Otolaryngology
Nephrology, Urology, Obstetrics & Gynecology, Pedatrics, Genetics

Objective:

ICD-10:

Description:

Juvenile Paget Disease (JPD) is associated with a mutation in the gene TNFRSF11B that results in defective osteoprotegerin, a protein involved in the regulation of bone turnover. A patient with Juvenile Paget Disease (JPD) may develop one or more ocular changes, some of which can lead to blindness.

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