Historical risk factors:
(1) long-term history of rheumatoid arthritis or other autoimmune disease associated with a risk of later malignancy
(2) history of exposure to carcinogenic agents (drugs, chemicals or radiation)
(3) evidence of another condition that could be a paraneoplastic disorder
Clinical findings:
(1) explosive onset of an asymmetric arthritis in an elderly patient (cancer polyarthritis)
(2) rheumatoid arthritis or Sjogren's syndrome with monoclonal protein or monoclonal lymphoid proliferation
(3) hypertrophic osteoarthropathy
(4) dermatomyositis
(5) atypical polymyalgia rheumatica
(6) Lambert-Eaton myasthenic syndrome
(7) palmar fasciitis and arthritis
(8) eosinophilic fasciitis that does not respond to corticosteroid therapy
(9) erythema nodosum that is present for more than 6 months
(10) onset of Raynaud's syndrome after 50 years of age
(11) onset of cutaneous leukocytoclastic vasculitis after 50 years of age
Additional findings (items from Table 1):
(1) adult onset Still's disease
(2) relapsing polychondritis
(3) cryoglobulinemia
(4) relapsing seronegative symmetric synovitis with pitting edema (RS3PE)
