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Noncirrhotic Portal Hypertension Associated with Antiretroviral Therapy

Purpose:

To identify an HIV-infected patient with noncirrhotic portal hypertension associated with chronic didanosine (DDI) therapy.

Specialty:

Gastroenterology
Clinical Pharmacology & Toxicology

Objective:

risk factors, complications

ICD-10:

K76.6, B23.0, K71.9

Description:

An HIV-infected patient may develop noncirrhotic portal hypertension following long-term antiretroviral therapy. Kovari et al were able to find an association between prolonged exposure to didanosine and this disorder. The authors are from the Swiss HIV Cohort Study.

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