Yang et al reported prognostic models for a patient with osteosarcoma. These made use of the pre-treatment Naples prognostic score. The authors are from Cancer Hospital of China Medical University in Shenyang, China.
Patient selection: osteosarcoma
Parameters:
(1) Enneking stage
(2) metastases
(3) local recurrence
(4) neutrophil to lymphocyte ratio (NLR)
(5) Naples prognostic score (NPS, from 0 to 4)
Parameters
Finding
Points
Enneking stage
I or II
0
III
34.9
metastases
no
0
yes
69.2
local recurrence
no
0
yes
51.8
NLR
<= 2.96
0
> 2.96
82.9
NPS
0
0
1 or 2
46.9
3 or 4
98.5
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 337.3
Score
Probability of 5-Year Survival
< 9
> 60%
9 to 208
(0.0000037029 * ((score)^2)) - (0.0036953 * (score)) + 0.647
> 208
< 5%
Score
Median Survival Time
< 25
> 65 months
25 to 286
(0.0002372 * ((score)^2)) - (0.24759 * (score)) + 71.76
> 286
< 20 months
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