Yang et al reported prognostic models for a patient with osteosarcoma. These made use of the pre-treatment Naples prognostic score. The authors are from Cancer Hospital of China Medical University in Shenyang, China.
Patient selection: osteosarcoma
Parameters:
(1) Enneking stage
(2) metastases
(3) local recurrence
(4) neutrophil to lymphocyte ratio (NLR)
(5) Naples prognostic score (NPS, from 0 to 4)
Parameters
Finding
Points
Enneking stage
I or II
0
III
50.9
metastases
no
0
yes
71.4
local recurrence
no
0
yes
43.9
NLR
<= 2.96
0
> 2.96
76.7
NPS
0
0
1 or 2
46.7
3 or 4
94.6
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 337.5
Score
5-Year Overall Survival
< 7.5
> 70%
7.5 to 229.1
0.7308 - (0.002782 * (score))
> 229.1
< 10%
Score
Mean Survival Time in Months
< 16.7
> 70 months
16.7 to 298.9
(0.0001183 * ((score)^2)) - (0.2198 * (score)) + 74.65
> 298.9
< 20 months
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