Wang et al reported nomograms for predicting cadmium-induced renal tubular dysfunction. One nomogram is for females. The authors are from Nanjing University and Fudan University in China.
Patient selection: exposure to cadmium, primarily in rice and leaf vegetables
Parameters:
(1) age in years, from 25 to 70
(2) blood cadmium concentration in µg/L, from 0 to 65
(3) total cadmium intake in µg/d, from 20 to 280
points for age =
= (1.21778 * (age)) - 30.44444
points for blood cadmium level =
= (1.538 * (blood level))
points for total cadmium intake =
= (0.1973 * (total intake)) - 3.9461
total score =
= SUM(points for age and blood level)
Interpretation:
• minimum score: 0
• maximum score: 206.12
value of X =
= (0.026246 * (score)) - 2.7013
probability of renal tubular dysfunction =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.74.
